The Harold E. Eisenberg Foundation


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Page 15 of 103

Sincerely, 14 A Letter from Our Doctors Dear Friends of the Harold E. Eisenberg Foundation, On behalf of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University and the patients we serve, it is our honor to thank the Harold E. Eisenberg Foundation for its continued partnership. We are ever grateful for your longstanding support of the Harold E. Eisenberg Gastrointestinal Cancer Tissue bank and of the vital work of our GI Oncology Research Nurse Coordinator. Your support of the Harold E. Eisenberg Research Scholar is invaluable. In the past year, the inaugural Harold E. Eisenberg Research Scholar, Guang Yu Yang, MD, PhD, aimed to develop a novel and effective strategy for the treatment of the highly lethal BRAF-mutant colorectal cancer, a disease with poor prognosis and elusive treatment options. Your funding has allowed Dr. Yang to utilize the Harold E. Eisenberg GI Cancer Tissue Bank and establish a colorectal carcinoma database of more than 300 cases, each with a comprehensive gene mutation profile. Dr. Yang has since used these findings in an application for a prestigious and competitive R01 Grant from the National Institutes of Health (NIH). The 2017-2018 Harold E. Eisenberg Scholar, Ronen Sumagin, PhD, is an assistant professor in the Department of Pathology whose research focuses on identifying new/improved therapeutical approaches aimed at resolution of mucosal inflammation. Inflammation is one of the key risk factors for colorectal cancer, and with the Foundation's support, Dr. Sumagin's laboratory aims to define the mechanism of action of these harmful factors, and to test whether neutralizing them can prevent increased mutations and cancer. Together, the Harold E. Eisenberg Foundation and Northwestern University are at a pivotal and fruitful moment in our partnership. We are excited to partner with the Foundation to launch the Harold E. Eisenberg Foundation GI Cancer OncoSET program at the Lurie Cancer Center in the coming year. Your commitment to this new initiative will advance our genomic profiling offerings for our sickest patients and will aid in the development of novel molecularly targeted clinical trials in GI cancers. We proudly thank the Harold E. Eisenberg Foundation for equipping the Lurie Cancer Center with crucial resources to further elevate our GI Oncology program and to establish Northwestern as a national and international leader in developing and providing effective, personalized gastrointestinal cancer treatment. Leonidas Platanias, MD, PhD Al B. Benson III, MD, FACP, FASCO Jesse, Sara, Andrew, Abigail, Benjamin and Elizabeth Lurie Professor of Medicine Professor of Oncology Associate Director, Cooperative Groups, Director, Lurie Cancer Center Lurie Cancer Center Philan T hro P y i n a CT ion Gastrointestinal Cancer Research

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